Four therapeutic genes have been inserted and one ‘unwanted’ gene removed from the DNA of preclinical models in a single intervention

Integra Therapeutics - ASGCT 2026

The Cell Engineering team at Integra Therapeutics has conducted a preclinical trial demonstrating the FiCAT platform’s ability to simultaneously insert up to four genes in a therapeutic payload into a defined, safe location in the genome, while deactivating an unwanted gene—all in a single step. These results are significant because current CAR-T cell therapy manufacturing […]

Integra Therapeutics appoints Miles Gerson as Independent Chairman

Miles Gerson

Integra Therapeutics announced today the appointment of Miles Gerson as the Independent Chairman of its Board of Directors. His incorporation strengthens the company’s governance and supports its strategic vision as it moves toward key development milestones. Mr. Gerson brings more than 20 years of experience in healthcare venture investing, business development, licensing, technology transfer and […]

Generative AI is more efficient than nature at designing proteins to edit the genome

Dimitrije Ivančić (co-first author of the paper), Avencia Sanchez-Mejías (CEO of Integra Therapeutics), Alejandro Agudelo (co-first author of the paper) and Marc Güell (ICREA researcher and CSO of Integra Therapeutics)

Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated new synthetic proteins that can edit the human genome more efficiently than proteins provided by nature. This work, a global pioneer published today in […]

Integra Therapeutics secures €10.7 million investment round to advance development of FiCAT gene writing platform and preclinical validation of CAR-T therapies

Integra Therapeutics, a global leader in cutting-edge gene writing tools to improve the efficacy, precision and safety of advanced therapies, announced it has closed a €10.7 million pre Series A round of investment. The funds come from new investors like the EIC Fund —the venture capital arm of the European Innovation Council (EIC) with the […]

Caszyme and Integra Therapeutics sign licensing agreement for novel CRISPR Cas12l nucleases

Caszyme and Integra Therapeutics

Caszyme, a pioneer in the development and application of CRISPR gene editing technology, and Integra Therapeutics, a company leading the way in creating advanced therapies based on next-generation gene-writing tools, today announced a licensing agreement for the use of Caszyme’s novel Cas12l nucleases to develop safer and more efficient gene and cell therapies. The agreement […]