Day: 13 May 2026

Four therapeutic genes have been inserted and one ‘unwanted’ gene removed from the DNA of preclinical models in a single intervention

The Cell Engineering team at Integra Therapeutics has conducted a preclinical trial demonstrating the FiCAT platform’s ability to simultaneously insert up to four genes in a therapeutic payload into a defined, safe location in the genome, while deactivating an unwanted gene—all in a single step. These results are significant because current CAR-T cell therapy manufacturing […]